宋肖垚

发布时间：2022-10-25 浏览次数：1956

宋肖垚女讲师

电话：0512-65880073

电子邮箱: xysong@suda.edu.cn

通讯地址：苏州工业园区仁爱路199号威尼斯欢乐娱人城精品一期医学楼医学院威尼斯欢乐娱人城精品402号2425室, 邮编215123

个人简介：

宋肖垚(Xiaoyao Song)，博士研究生学历，医学博士学位

学习经历

2004.9‒2009.7哈尔滨医科大学预防医学专业医学学士

2009.9‒2015.12哈尔滨医科大学卫生毒理学医学博士

工作经历

2016.3‒2022.1中国科学院大连化学物理研究所博士后/助理研究员

研究方向：

应用多组学策略研究环境污染物对机体毒作用机制的研究

科研项目：

1.国家自然科学基金青年基金，代谢组学策略探究PM_2.5关键毒作用组分对抑癌基因P53依赖的代谢毒性及其分子机制,21806165,2019.01-202.12; 27.5万元,主持

2.国家博士后基金(第60批)：面上项目，PM_2.5对人肺上皮细胞毒性作用机制——代谢组学分析策略,2016M601352，2017/01-2017/11，8万元,主持

3.国家自然基金重大研究计划重点支持项目, 大气细颗粒物的毒理与健康效应, 91543201, 2016.01-2019.12，336万，参与

4.国家自然科学基金培育项目，91643104，高分辨质谱技术鉴定大气细颗粒有机组分及其呼吸系统损伤，2017/01-2019/12，90万元，参与

专利：

一种用于非暴露式气管滴注的实验鼠固定装置. 2018-11-30，中国，ZL201822003146.8.
一种精确定量非暴露式气管滴注装置. 2018-11-30，中国，ZL201822008690.1.

代表性论著:

《环境化学前沿(第二版)》第十五章，2019年，科学出版社

代表性论文（*通讯作者）：按照引文格式

1.Xiaoyao Song¹, Jianhui Liu¹, Ningbo Geng, Yichu Shan, Baoqin Zhang, Baofeng Zhao, Yuwen Ni, Zhen Liang, Jiping Chen*, Lihua Zhang*, Yukui Zhang. Multi-omics analysis to reveal disorders of cell metabolism and integrin signaling pathways induced by PM_2.5. Journal of Hazardous Materials. 2022. IF: 14.224

2.Zhigang Sui¹, Xiaoyao Song¹, Yujie Wu, Rui Hou, Jianhui Liu, Baofeng Zhao, Zhen Liang, Jiping Chen, Lihua Zhang*, Yukui Zhang. The Cytotoxicity of PM_2.5 and its Effect on the Secretome of Normal Human Bronchial Epithelial Cells. Environmental Science and Pollution Research, 2022. IF: 5.190

3.Xiao-Yao Song, Jia-Nan Li, Yan-Ping Wu, Bo Zhang, Bai-Xiang Li*. Atrazine Causes Autophagy- and Apoptosis-Related Neurodegenerative Effects in Dopaminergic Neurons in the Rat Nigrostriatal Dopaminergic System. Int. J. Mol. Sci. 2015, 16, 13490-13506. IF: 6.208

4.Ningbo Geng, Xiaoyao Song, Rong Cao, Yun Luo, Mila A, Zhengang Cai, Kejie Yu, Yuan Gao, Yuwen Ni, Haijun Zhang, Jiping Chen*. The effect of toxic components on metabolomic response of male SD rats exposed to fine particulate matter. 2021. Environ Pollut. IF: 9.988

5.Yun Luo, Baoqin Zhang, Ningbo Geng, ShuaiSun, Xiaoyao Song, Jiping Chen, Haijun Zhang*. Insights into the hepatotoxicity of pyrene and 1-chloropyrene using an integrated approach of metabolomics and transcriptomics. Science of the Total Environment, 2022.IF: 10.753

6.Yun Luo, Baoqin Zhang, Ningbo Geng, ShuaiSun，Xiaoyao Song，Jiping Chen*，HaijunZhang. Transcriptomics and metabolomics analyses provide insights into the difference in toxicity of benzo[a]pyrene and 6-chlorobenzo[a]pyrene to human hepatic cells. Accept. Science of the Total Environment, 2022. 10.753

7.Ningbo Geng, Yun Luo, Rong Cao, Xiaoyao Song, Fang Li, Feidi Wang, Yufeng Gong, Liguo Xing, Haijun Zhang, Jiping Chen*. Effect of short-chain chlorinated paraffins on metabolic profiling of male SD rats. Science of the Total Environment, 2021, 750: 141404. 10.753

8.Xiaoqian Ren, Ningbo Geng, Haijun Zhang, Feidi Wang, Yufeng Gong, Xiaoyao Song, Yun Luo, Baoqin Zhang, JipingChen*. Comparing the disrupting effects of short-, medium- and long-chain chlorinated Paraffins on cell viability and metabolism. Science of the Total Environment, 2019, 685: 297-307. IF: 7.963

9.Yufeng Gong, Haijun Zhang, Ningbo Geng, Liguo Xing, Jingfeng Fan, Yun Luo, Xiaoyao Song, Xiaoqian Ren, Feidi Wang, Jiping Chen*. Short-chain chlorinated paraffins (SCCPs) induced thyroid disruption by enhancement of hepatic thyroid hormone influx and degradation in male Sprague Dawley rats. Science of the Total Environment, 2018, 625: 657-666.IF: 6.551

（以上内容系教师个人提供）